Ronny Deila has tended to prefer to play just one up front this season.
With Deila preferring to use a lone striker so far this season, and with Griffiths in such ruthless form, Ciftci's chances have been limited since his summer move to Parkhead.
The 23-year-old had also received criticism for some of his performances, and Cascarino - whose time at Celtic reaped just four league goals in 24 games - admitted that he had sympathy for the former Dundee United man's situation.
"The one position where you really need to be playing all of the time is striker because you need that fitness and sharpness," he said.
"If you are not playing it’s hard to be at your best and that has clearly been the case with Ciftci.
"Sometimes it takes a player to get injured to give you the opportunity but it's tough, especially with so many managers playing with one up."
However, he silenced many of his critics with a brace against St Johnstone that guided the Bhoys to a 3-0 win, and certainly gave his manager something to think about going forward.
Cascarino believes that with Celtic in such command of the Premiership, it would be a mistake on Deila's part not to utilise both strikers in the same team.
"Celtic should be playing with two up front against the majority of teams in the Scottish Premiership," he claimed.
"They are the strongest side and there should surely be room to go in that direction, even now and again, which would let Griffiths and Ciftci play," he explained.
While it may be tempting to throw both of his most lethal strikers onto the pitch at the same time, in the hope that it ends the title race before it really gets going, there is certainly a risk of upsetting the apple cart a little too much.
Celtic's system has been working for them in the league in recent weeks, and while they are in a strong position for now, a bizarre run of results could bring Aberdeen back into the title picture.
The idea of sticking Griffiths and Ciftci together may look great on paper, but if the pair are unable to play together then it may dent their individual form, and leave Deila wondering why he deviated from plan A in the first place.