“I watched West Ham against Tottenham when they went away and without Payet, they miss him,” he told Sky Sports.
“I can see that one being a tight one, but I still think West Ham will win.”
West Ham head into the encounter at Old Trafford on the back of a 1-1 draw with West Bromwich Albion at Upton Park last time out.
The draw with the Baggies was their third game in a row without a win, having been beaten by Tottenham Hotpsur before that and drawn with Everton prior to the international break.
Slaven Bilic’s side are currently eighth in the table with 22 points from 14 games.
They are eyeing up a potential European spot at the end of this season, with Liverpool just a point ahead of them in sixth and Tottenham two points ahead in fifth place.
In contrast, United are third in the table with 28 points from 14 games, and fully eyeing a title challenge this year.
They are just one point off of Manchester City in first place, meaning they are definitely in the race for the top-flight crown.