Defenders Wilson and Mancienne came on as substitutes in the second half in the Championship game against the Royals at the City Ground on Saturday afternoon.
The duo played an important role in keeping things tight at the back, as the Reds won the encounter 3-1 despite the dismissal of Jack Hobbs.
“I’ve got to give credit to the substitutes,” Freedman told Forest’s official website. “Kelvin Wilson hasn’t been playing of late, Michael Mancienne has been missing, but they came on and got right into the thick of the action - putting their heads where it mattered.”
Over the course of the 90 minutes at the City Ground, hosts Forest had 44% of the possession, took 12 shots of which five were on target, and earned four corners.
Forest are 16th in the Championship table at the moment with 20 points from 18 matches, just five points above the relegation zone.
The Reds will return to action next weekend when they take on Fulham at the City Ground in the league.