The striker says it would be nice to bag another hat-trick against Jose Mourinho's side.
The duo head into the London derby in contrasting scenarios, with both having had vastly different starts to their respective campaigns.
In contrast Chelsea find themselves way down the table in 15th in place, with the defeat of Norwich last weekend ending a run of back-to-back defeats.
It will still be a tough game for Spurs, but Kane has said that they know exactly what they must do.
“I feel fit and I wanted to come and play. I’m delighted to score,” he told BT Sport. “I’m feeling confident, every game that comes along I feel like I’m going to score, as a striker you just want the games coming thick and fast.”
“It would be nice to score a hat-trick [against Chelsea], but it’s going to be a tough game. We know how we’ve got to play; we’ve got to take the game to Chelsea.”
The game against Chelsea is sure to be a big one for Spurs, as a win could determine their Champions League credentials.
While the Blues are not the force they were last season, beating them would still prove a huge boost to Pochettino’s side, as it was last season.
Aside from that, it would also help them to continue their fine form this season, and maintain their winning streak as the season heads into the crucial Christmas period.