The Belgian has stated that the clash with the Hammers is one his side want to win.
The Hammers have been in good form on the road however, winning against Liverpool, Arsenal and Manchester City this season already.
Alderweireld has stressed that his side will enter into the game in confident mood after recent results, but it wary of the threat that West Ham pose.
“It’s a big challenge because West Ham are playing very well and they are near the top places in the league with us,” the Belgian told the club’s official website.
“They’re a very good team so it’s going to be difficult for us, but we are in a good moment as well. Everybody is doing well and there is a lot of confidence among us, but I feel we are not over-confident.
“We are where we are because we work hard and when we do that our quality can make the difference. The first thing we have to do is work hard and that’s what we’re going to do on Sunday.”
Alderweireld’s arrival at White Hart Lane and subsequent central defensive pairing with compatriot Jan Vertonghen has been an overwhelming success so far this season for Spurs.
The Belgian pair will have their hands full with Andy Carroll likely to lead the line for the visitors this afternoon.
Spurs will know they will need to be at their best, with a 3-0 defeat in the same fixture back in 2013 still fresh in the memory.