Spurs welcome the Belgian side to White Hart Lane.
There was some good news for one Spurs player earlier today. Eric Dier received his first call-up to the England senior team from Roy Hodgson. He will hope to celebrate with a start.
Andros Townsend is of course not involved. He was involved in a bust-up with the Spurs fitness coach at Villa Park on Monday night leaving him out of contention because of disciplinary reasons.
Heung-min Son looks set for a place on the bench as he steps up his recovery from injury whilst youngster Josh Onomah will be hopeful of getting onto the field again at some point this evening.
It will also be interesting to see if Mauricio Pochettino chops and changes the team at all - with the North London derby approaching.
Here is the Spurs team for tonight's game: