Blankfein disclosed in September that he has a "highly curable" form of lymphoma that will require treatment. Since then, he's kept a low public profile as Wall Street wondered about the condition of one of its most familiar faces.
Speaking at the DealBook conference, Goldman 's president and chief operating officer, Gary Cohn, said his boss is fine.
Read More Goldman CEO Lloyd Blankfein has lymphoma
Blankfein takes the attitude that getting through the disease is "just another chore, just another task, and I'll get through it."
"He's in the office every day, he's engaged," Cohn said. "The days he's not in the office, he's on the phone all day long and the relationship has never been better."
Goldman's stock has been performing well in the days since Blankfein disclosed his health problem, rising more than 10 percent along with the market since the late-September lows.
Cohn said the company is continuing to function at a high level.
"We have a very deep bench," he said. "There's not a problem at Goldman Sachs. If anything, it's giving people opportunities to do things they might not have the opportunity to do."