Leeds will host Cardiff in the Championship at Elland Road, and Holloway has backed the Bluebirds for a 2-1 victory.
“Cardiff have got the tools to go to Elland Road and win,” the former Queens Park Rangers boss wrote on Skysports.com. “They have the squad to challenge at the top.”
Leeds are 19th in the Championship table at the moment with 13 points from 14 matches, just three points above the relegation zone.
The Whites will head into Tuesday evening’s match on the back of a 2-0 defeat to Blackburn Rovers at Elland Road.
Meanwhile, Cardiff currently find themselves ninth in the standings with 22 points from 14 matches, just two points behind sixth-place Birmingham City.
The Bluebirds will head into the match against Leeds on the back of a goalless draw with Ipswich Town away from home at Portman Road.
Leeds are winless in their last 16 league encounters with Cardiff, losing 11 and drawing five.