Indeed, the Argentine succeeded at the Spanish club for a number of years but eventually left with the team in a sorry state.
And the Tottenham boss says the pressure became 'unbelievable' at the club. Espanyol urged Pochettino to create the next young star to sell, he says, and he was happy to join Southampton later in his career - once he had left Espanyol - to avoid similar problems.
Pochettino is quoted as telling reporters: "After five seasons at Espanyol the pressure was unbelievable.
"I was a player at Espanyol for 12 years and I played the most games for the club. The pressure was higher, because the pressure was to create a player from the academy, to try to save the club, by selling the player on.
"But then you rebuild the team every six months. The supporters are ambitious and they say, 'We are in the top ten every season, why are we not now in the top six and playing in the Europa League?' Well, yes - but our project has not yet arrived at that point.
"After five seasons it's difficult to keep the motivation - and for us it was difficult. So when the chance to go to Southampton came it was a dream."
At Tottenham, Pochettino certainly won't be under pressure to produce players and sell them from the academy. But he may well see his best stars leave if a huge club comes in for them.
It was a similar situation for him at Southampton, while both Spurs and Saints fans will also be expecting their sides to push for high finishes.
It is generally accepted that the Argentine did a good job at Espanyol until the club became more cash strapped than previously and he had his best players sold.
His long-term reputation will no doubt be defined by the success he achieves at Tottenham.