The France international centre-back looked as though his days were numbered at Anfield in the summer, when he was left out of the the first three games of the new campaign.
Dejan Lovren was preferred ahead of Sakho by former manager Brendan Rodgers as the Northern Irishman tried to give the Croatian international a chance to justify a hefty price-tag that had looked like a monumental waste of money in the ex-Southampton defender's debut campaign at Anfield.
However, defeat to Manchester United back on September 12, saw Lovren axed from the side in favour of Sakho, and the ex-Paris Saint-Germain man hasn't looked back since.
Rumours of a switch to Roma - reported in the Telegraph - were emphatically squashed when he signed a new five-year contract with the Reds just 24 hours after being handed the skipper's armband for the first time in the 1-1 Europa League draw with Bordeaux on September 17.
The powerful defender's gangly frame sees him singled out for ridicule at times in possession, but the 25-year-old is an accomplished passer over short distances - he knows his limitations and doesn't try to break out of them - a trait that Lovren cannot be credited with.
Henderson's appointment as captain following Steven Gerrard's departure was generally greeted warmly by the club's fans, as was Milner's as vice-skipper, but the free transfer from Manchester City is currently enduring a poor run of form since moving to Anfield.
Milner could do with a spell without the armband as he tries to settle into life at a club with often suffocating expectations, and in the continued absence of Henderson, Sakho is the ideal man to take the honour - his influential qualities saw him handed the captaincy at PSG at just 17 to make him the youngest skipper in the Ligue 1 side's history.
The centre-back was once again impressive as Jurgen Klopp's men were held to a disappointing 1-1 draw with Rubin Kazan on Thursday, but it was the German's first game away to Tottenham Hotspur on October 17 where the defender really shone.
Sakho marshalled the lively Harry Kane throughout and saved his side with a superb block to deny a goal-bound effort in the first half at White Hart Lane.
Henderson is currently expected to be sidelined until November with a metatarsal injury - and in the absence of the tireless England midfielder, it is time Sakho was made captain.