The Spurs boss must utilise his squad more effectively this season.
Tottenham Hotspur’s failure to secure three points away at Monaco in their last Europa League outing has meant the pressure to securing two wins from their upcoming double-header with Anderlecht has increased.
The Belgian club have been poor in Europe and currently sit bottom of the group on one point after losing to Qarabag in their second game.
Spurs will be confident of grabbing the six available points but a sensible approach is needed from Mauricio Pochettino, and he must take care that his determination to qualify early doesn’t affect the Lilywhites’ domestic form.
Injuries to Heung-Min Son, Nacer Chadli and Alex Pritchard have reduced his options in attack, but the squad still boasts enough quality to allow their key men a rest.
Harry Kane has yet to get going this season and there is an argument that playing him in the Europa League – where goals are theoretically easier to come by – could be a benefit, but his play style makes that unlikely.
The 22-year old is renowned for his work ethic and looks noticeably exhausted in the closing stages of games.
A midweek rest - so he is fit and firing for the weekend - would be sensible, and Pochettino has the players to cope.
Clinton N’Jie is familiar with a central striking role and has electric pace capable of worrying any defence.
Playing Lamela behind the Cameroonian would also allow Christian Eriksen a rest and put the Argentine in his most effective position.
Andros Townsend slots comfortably into the right flank position and will be determined to produce the goods after an indifferent start to the season.
In the absence of Nacer Chadli, Dele Alli could be utilised from the left - given he has proven his effectiveness in a more advanced role already this season.
A dynamic, interchangeable attacking four of N’jie, Lamela, Townsend and Alli should be enough to see off an average Anderlecht side and most importantly, will allow Tottenham’s two main men a night off.
Eric Dier’s return to central defense would give Toby Alderweireld a rare rest and Kevin Wimmer will be hoping for a start after missing out against Monaco.
Tom Carroll and Mousa Dembele would be enough to cope in the middle, while Ben Davies and Kieran Trippier should deputise for Danny Rose and Kyle Walker.
See the full team below: