Leeds United travel to Elland Road to face Fulham this evening.
Leeds are visitors to Craven Cottage later today, and the match will be Steve Evans' first as manager of the Whites.
And Symons admits that he is in the dark as to how Leeds might set up, with much of his preparation for the game rendered useless by Leeds' latest managerial change.
"It'll be interesting, we're not quite sure what to expect," he said. "We've done our work on Leeds, but with a new manager he could come in and completely change their style of play. It'll be interesting to what he does.
"We're still playing against Leeds United, and they have the same group of players that they had last week. They have some really good players in their squad, but I'm confident we can beat them."
Evans has told the Yorkshire Evening Post that he is likely to set-up with a 4-4-2 formation for the fixture, and he has also suggested that he wants to make Leeds play with more aggression.
However, there have been very few hints over who he might select for the fixture, and it is unknown how much tinkering he wishes to do with Leeds' line-up.
The Whites have lost their last three fixtures, meaning that Evans takes over a squad which is in poor form, and could be low on confidence.
He will be hoping that his initial time with them can spark some improvement though, as a win could push the Yorkshire club up as high as 13th in the Championship table.