Klopp has been appointed as the new Reds boss following the departure of Brendan Rodgers, and there is plenty of anticipation as he prepares for his first game - a daunting trip to White Hart Lane.
Liverpool have a great record away at Spurs in recent years, but Mauricio Pochettino's men have lost just once in the Premier League this season, with a youthful side earning great results so far this term, such as the 4-1 home win over Manchester City.
Still though, they only sit one point ahead of Liverpool in the Premier League table, something that seems to have flown under the radar amid all the excitement over Klopp's arrival.
The German comes in with a huge reputation from his time at Borussia Dortmund, and whilst he has two Bundesliga titles to his name, today is his first test in the Premier League, and it's far from an easy start to life in English football.
The game at White Hart Lane should be a close-fought one, and BBC pundit Mark Lawrenson believes that the game will end in a draw - before stating that Klopp should look to imitate Tottenham boss Pochettino may simply making his side hard to beat, given that he believes Spurs are the better side heading in to today's clash.
"I have never known a managerial appointment to get the kind of universal approval from fans that Jurgen Klopp has been given at Liverpool," said Lawrenson. "I can see why he is has endeared himself to the supporters straight away, because his style is in-your-face, attacking football. When you look back to all the top Liverpool teams, that is how they played."
"He is not going to turn things round overnight, though, especially because his first game is against a Tottenham team who have not lost in the league since the opening day and are on a really good run. Spurs are the better team at the moment and will think they have a good chance of ruining Klopp's party."
"I see it being a draw, but the really interesting thing for me is how Klopp will set his team up. He has got some decisions to make in terms of his team selection but, from listening to him, the first thing he will do is make them difficult to beat. That is what Mauricio Pochettino has done at Spurs, but you could argue it is what Klopp's predecessor at Anfield, Brendan Rodgers, did not do," he added."