Everton v Manchester United (October 17)
Manchester United will be determined to bounce back from the 3-0 defeat to Arsenal at the Emirates Stadium before the international break.
While the Red Devils have better players than Everton, Roberto Martinez’s side are strong at home and have lofty ambitions of their own.
It will be tough for United to win the match at Goodison Park, but they should be able to pick up a point.
Everton 1-1 Manchester United
Manchester United v Manchester City (October 25)
The Manchester derby is one of the biggest games in English football calendar, and the match at Old Trafford later this month is going to be a huge one.
Both United and Manchester City are aiming for the Premier League title this season, and both sides like to play attacking football.
The form book will go out of the window for this match, but it is hard to see City lose. A draw is the most likely outcome.
Manchester United 2-2 Manchester City
Crystal Palace v Manchester United (October 31)
Crystal Palace are fast proving to be the surprise package of the 2015-16 Premier League campaign, but they are unlikely to defeat United at Selhurst Park.
While Alan Pardew’s side are strong at home, Louis van Gaal’s United team have better players and should have enough to pick up all three points in London.
Crystal Palace 0-2 Manchester United
Manchester United v West Bromwich Albion (November 7)
West Bromwich Albion are struggling at the wrong end of the table, although things could change between now and November 7.
United should still have enough to defeat the Baggies pretty comfortably and maintain their chances of winning the Premier League title this campaign.
Manchester United 3-0 West Bromwich Albion