Indeed, the old saying that you win your home games and draw your away fixtures is lost on the Argentine, who is not prepared to change his approach against the Ligue 1 side.
Tottenham beat Qarabag at White Hart Lane during their first Europa League clash of the season and naturally head into the Monaco clash full of confidence after their 4-1 win over Manchester City.
That has left Pochettino refusing to settle for anything less than a win, as reported by Spurs TV. When asked if he could approach an away game going for a draw, he said:
"We need to take the three points. It's important because Anderlecht and Qarabag are very good teams, too. We want to take all three points and try to win."
Europe provides tricky territory and Monaco are no slouches. As their win at the Emirates last season showed - as well as the Champions League results of English teams so far this term - going for the win against such opposition can always backfire. It’ll be a risky strategy from the Spurs boss.
But Tottenham’s Manchester City win is the biggest recent proof Pochettino’s men can simply outplay the opposing side. So is Poch right to reject the chance to play safe for a point?