Tottenham Hotspur’s second Europa League group stage encounter sees them travel to the south of France to take on a decent Monaco side at the Stade Louis II.
With a visit to Swansea City on Sunday in mind, Thursday’s trip to Monaco is a real tough one for Pochettino, and his side’s line-up could look very different from last weekend.
With the Premier League a priority, Spurs ought to rest players and keep in mind that even though defeat in Monaco would be disappointing, they’re still in a good position to qualify.
Goalkeeper Michel Vorm ought to come in for some much-needed minutes, while full-backs Kieran Trippier and Danny Rose are expected to feature ahead of regulars Ben Davies and Kyle Walker.
Pochettino, however, would be wise to stick with Toby Alderweireld and Jan Vertonghen in the middle as the Belgian duo are still in the process of building a solid centre-back partnership.
Eric Dier’s immense performances in a defensive midfield role have seen him become somewhat irreplaceable at the moment, especially considering Ryan Mason and Nabil Bentaleb are out injured.
The former Sporting Lisbon ace should be rested ahead of the Swansea City clash, with Dele Alli and Tom Carroll capable of coming in and playing as a midfield two.
It’s a pity Mousa Dembele and Alex Pritchard are injured, as Spurs’ attacking options become thin and the opportunity to rest key players perhaps isn’t quite there at the moment.
With Harry Kane expected to lead the line, the England international ought to be accompanied by Heung-Min Son somewhere in the attacking third in order to further boost their on-field relationship.
Erik Lamela and Christian Eriksen can be afforded a rest ahead of the trip to Swansea’s Liberty Stadium, with Andros Townsend and Nacer Chadli suitable alternatives in the wide positions.