Southampton take on Milton Keynes Dons tonight in the Capital One Cup.
The Saints are playing their first game in this year's competition against the Dons, and Koeman insists that he wants to see his troops embark on a positive run.
However, the Dutch manager is not prepared to put out his strongest team - as he wants to give his fringe players the opportunity to impress.
"That can be, one or two more changes than normally we did last year but that’s all about the competition that we have in the squad," he said.
“Everybody is working hard to get the chance to play, it’s all about maybe some little injuries to protect a player and to have everyone available and have everyone 100 per cent. It’s not changing because you like to change, I like to go on in this tournament and to put a strong team to beat them.
“It’s always opportunities for players who are maybe not very involved in the last few games.”
It could be a good chance for some of Southampton's lesser utilised players to stake a claim for a place in the starting line-up, as the side has struggled so far.
Southampton have set their standards high over recent years, but they have not got going yet - with their performances uncharacteristically poor.
The South Coast outfit have found wins hard to come by over the campaign to date, and they sit in 16th place in the Premier League table.
It means that there could be places up for grabs tonight, and a strong performance against the Dons could give Koeman something to ponder ahead of the side's weekend meeting with Swansea City.