He will be working 'substantially as normal, leading the firm'.
"Late this summer after several weeks of not feeling well, I underwent a series of tests, which culminated in a biopsy last week," Blankfein said in a release. "Fortunately, my form of lymphoma is highly curable and my doctors' and my own expectation is that I will be cured."
Blankfein added that he will be able to "work substantially as normal, leading the firm" while undergoing treatment, but will "reduce some of my previously planned travel during the treatment period. I have discussed this approach with our Board of Directors and they are supportive."
Goldman Chief Operating Officer Gary Cohn will have enhanced responsibilities while Blankfein undergoes treatment, a source told CNBC.
This story is developing. Please check back for further updates.
Click here for the latest on the markets.