The Belgian midfielder has stated that he was frustrated at losing to West Ham, but is fitting in at the club well.
The former Wolfsburg man got the opportunity to play centrally in Manuel Pellegrini’s team after David Silva picked up an injury in the warm-up, but couldn’t help his side in a 2-1 loss to the Hammers.
De Bruyne has stated that it was frustrating to not be able to break the visitors down, but that it was a lesson for the future.
"We tried everything to put pressure on them," the Belgium international told FourFourTwo.
"In the second half they didn't create one good chance. Maybe our last pass wasn't good but we didn't play badly.
"We didn't start well or defend well for their two chances. We have to learn from this.”
De Bruyne has returned to English football after a botched stint at Chelsea, but is a much improved player after stellar showings in the Bundesliga with Wolfsburg.
The gifted attacking midfielder has stated that he is happy with the way that he is fitting in at the Etihad Stadium and is targeting success with Pellegrini’s side.
"I try to do everything today to help the team, but it wasn't enough. I am happy with how I am integrating,” he continued.
"In a few weeks when I am settled it will be even better for me.
"If you lose these games you have to go on quickly. We tried to have a good reaction after Juventus but now we go on to Tuesday.”
City are expected to be one of the frontrunners for the Premier League title this season, with defeat against Slaven Bilic’s side the first dropped points of the campaign.