Sturridge returned to full training last week after undergoing hip surgery towards the end of last season, while Henderson is due to train with the side ahead of the game having had treatment in the USA on a problematic heel injury which has kept him sidelined since mid-August.
The Reds' boss explained how much of a miss the two players have been, saying at a press conference covered by the Liverpool Echo: "A player who can get you 25 plus goals in a season is going to be missed.
"Jordan's impact has grown during my time here.
"When you miss players of that calibre it's going to have an impact."
The Reds return to Premier League action desperate to get a win against the Canaries after back-to-back defeats scuppered what looked to be a promising start to the season.
Rodgers told reporters that the side don't have as many points as he would have liked from their opening five games, but has spoken about what could bring goals to the team and start getting the best out of them, believing that Sturridge alongside Christian Benteke could be an 'exciting dynamic'.
He said: "It's an exciting dynamic to have both Benteke and Sturridge. We've been waiting on that."
On Sturridge in particular, Rodgers commented: "On his game he's one of the best there is. He can stretch teams, and has wonderful variety in his finishing."
Thursday night saw a couple of first team players play alongside several youngsters in the Europa League, as the Reds kicked off their campaign with a 1-1 draw in Bordeaux in what Rodgers described as an encouraging performance.
Adam Lallana returned to the side from a thigh injury and scored the Reds' goal as well as completing 90 minutes, something which pleased his manager.
Rodgers also reaffirmed that the performance of Mamadou Sakho in France has given him something to think about, and said he is definitely in contention to face Norwich.
"It's a decision that I want. He's working hard, immaculate in training, peak fitness. His performance was brilliant."