A look at five players Tottenham should start against FK Qarabag.
The game offers a chance for Mauricio Pochettino to rotate his squad, with a Premier League clash with Crystal Palace three days later.
It could well have been a match the boss has had his eye on for a while with a view to making changes, and there are three exciting players all hoping for their first ever starts for the club.
Here is a look at who could be in...
Central defender Kevin Wimmer has had to bide his time since joining the club from Koln in the summer. He has sat behind first choice duo Toby Alderweireld and Jan Vertonghen, but could get his opportunity to stake a claim this evening. Wimmer is an Austrian international hoping to force his way into his country's side for Euro 2016, and there will be questions from fans if he is overlooked again for Spurs.
Another player in a similar position to Wimmer, Kieran Trippier signed in the summer from Burnley and was given chances in pre-season but has had to wait for a chance. The right-back is behind Kyle Walker in the pecking order, but is seen as very adept defensively and should be a safe selection not to let the side down on his debut.
Surely the most exciting of the five, Spurs fans have had to bide their time to see new signing N'Jie in action. The versatile forward is a potential game changer and this could be the perfect situation to announce himself at White Hart Lane. He is used to playing in European competition with Lyon and despite his young age is unlikely to be daunted by the challenge.
It's amazing really that a player as talented as Alex Pritchard is still waiting for his first Tottenham start. He has made one substitute appearance for the club this season, and if not selected in the XI, should at least make the bench. The former Brentford loanee could also be involved against Arsenal in the Capital One Cup next week, and Pochettino will have to balance his team selection with his wishes for that game, and the Premier League match with Crystal Palace in between.
Perhaps the longest shot of all five, 18-year-old midfielder Josh Onomah is on the fringes of the first team. Pictured in the club's first team squad photo earlier this week, this could be breakthrough season for him. The under-21 regular could get the nod in the midfield if Pochettino feels he can find a balance of youth and experience.