The company said these vacated roles will come mostly from the organization's Enterprise Services (ES) transformation.
In order to achieve savings, Hewlett Packard Enterprise expects 25,000 to 30,000 people to leave the company, HP said in a Tuesday press release.
The company said these vacated roles—about 10 percent of the workforce for the new corporation—will come mostly from the organization's Enterprise Services (ES) transformation.
"These restructuring activities will enable a more competitive, sustainable cost structure for the new Hewlett Packard Enterprise," Meg Whitman, HP's current chairman, president and CEO, said in a press release. "We've done a significant amount of work over the past few years to take costs out and simplify processes and these final actions will eliminate the need for any future corporate restructuring."
These are new, previously unannounced cuts, that the company expects will save about $2.7 billion.
HP is splitting into two listed companies—HP Enterprise and HP Inc.—later this year, separating its computer and printer businesses from its faster-growing corporate hardware and services operations.
—CNBC's David Faber and Reuters contributed to this report.