The Mexican forward’s future is in Germany after falling out of favour under Louis van Gaal.
The Mexico international has been at Old Trafford for five years and was a firm favourite of Sir Alex Ferguson.
However, following the appointment of Louis van Gaal, Chicharito slipped down the preference and spent last season out on loan at Real Madrid.
The chance to move to the BayArena will give the sprightly forward more of an opportunity to play regularly, with Leverkusen also competing in this season’s Champions League.
For United, the sale of Hernandez, who is the only real back-up option for Wayne Rooney in the number nine role, suggests that the club will conclude a deal for a new striker before the transfer window closes today.
BBC Sport suggest that a deal for Monaco’s Anthony Martial is all but done, which will boost Van Gaal’s options in attack.
"It's wonderful that I get to play for a club like Bayer Leverkusen. It's a great opportunity for me and I want to achieve something here.”