Mauricio Pochettino is thought to be keen on a reunion with the imposing midfielder.
Successive summers have seen the Saints lose their key assets and they are reticent to let their midfield general go, after the sale of Morgan Schneiderlin.
Lamela’s inclusion in the deal will hardly be the most attractive proposition either, given his shortcomings in the Premier League, while the player’s agent has admitted - as quoted by the IB Times - that a departure from England is probably in the 23-year old’s best interests,.
Spurs are in the market for an experienced central midfielder and have been strongly linked with Axel Witsel in the last 24 hours, but Pochettino has the added benefit of working with Wanyama already and that fact could make him a priority.
Both players would be an upgrade to Tottenham's first XI and it remains to be seen whether either deal can be agreed before the close of the window.