Michael Owen is predicting a draw this weekend at Selhurst Park.
The former England striker told Bet Victor that he believes Crystal Palace will at least hold them to a point.
Palace were impressive in their opening game of the season, beating Norwich 3-1 away from home.
Tipping a recommended bet of a double chance on a Crystal Palace win or a draw, he commented: "The Gunners have beaten Palace in each of their last five PL games but I like the look of this new Eagles’ side and don’t expect them to lose what promises to be a cracking London Derby."
Arsenal were narrow victors against Palace on both occasions last season, needing a late Aaron Ramsey goal to win at The Emirates a year ago, and just about managing an away win last season with Glenn Murray hitting the woodwork late on.
Arsene Wenger will hope for better performances from Petr Cech and his backline, after a disappointing 2-0 loss to West Ham at home in their first match.
Having come into the season labelled as title contenders, being winless after two games would be concerning for the Gunners, while this is exactly the type of match for Palace to underline why they are the surprise package for many.