The Reds defender has stated that his team must put the 6-1 loss on the last day of 2014-15 out of their minds.
The Merseyside outfit ended last term with a sizeable loss at the Britannia Stadium, sending club legend Steven Gerrard away from his boyhood team in underwhelming circumstances.
Brendan Rodgers’ men will have the perfect chance to right the wrong at the weekend, as Liverpool once more travel to face the Potters on the opening day of the new campaign.
Skrtel has admitted that the heavy defeat was embarrassing but is confident that the club are better positioned to get a positive result this time round.
“That was a very bad day for each of us,” Skrtel told The Liverpool Echo.
“It was embarrassing, not just because of the result but also because of the way we played.
“Obviously we can use that as motivation to drive us on into this season. However, this will be a different game and a different season.
“I am pretty sure we will be stronger and better this time. We have to forget about the last game there and start from the beginning again.
“You cannot do anything about who you are given to play in the first game. You have to accept it.
“We have to start the season somewhere so we must make sure we go to Stoke, start well and have a different outcome.”
Liverpool are under pressure to start the new campaign strongly, especially after missing out on their objectives last term and spending big in the off-season in a bid to get back amongst English football’s elite.
The Reds look set to have a considerably different team this weekend to the one that lost at Stoke back in May, with three valuable Premier League points on the line.