The winger has dismissed the Irishman’s comments that the Gunners were more concerned about selfies and six-packs than winning silverware.
The North London side won the Community Shield against Chelsea at the weekend, but their triumph was treated with derision from the former Manchester United enforcer.
The Irishman was critical of Arsenal’s title chances, accusing some of the players of having their priorities wrong.
Keane was used to having the North London side as his major rival in his days at Old Trafford, but Arsenal have had to watch on of late while other sides lift the title.
However, Oxlade-Chamberlain, who scored the winning goal against the Blues with a thunderous left-footed drive, has dismissed Keane’s claims and suggested that the Irishman was living in the past.
"It's a new era, isn’t it? Some people do it, some don’t," FourFourTwo quote the winger as saying.
“We’re serious about winning trophies. Personally, and I can speak for the rest of the squad, we’ve been serious every single year I’ve been at the club about winning trophies.
"You can see that on the pitch. A lot of people don’t see when we lose and go through tough times how upset and disappointed we are. We’ve always wanted to win trophies and in the last years we’ve won a few. This season we want to go that one better."
Arsenal have been the nearlymen of English football since their title triumph in 2004, with Arsene Wenger’s side threatening to win the Premier League but failing to deliver consistency on a number of occasions.
The Gunners put in a late run of excellent form last season to power up the table, but inconsistency early in the campaign ended up costing them.