D'Ambrosio, 26, signed for Inter from Torino 18 months ago, and has racked up over 40 appearances for the Italian giants during his time with the club.
However, the right back could now be pushed down the pecking order at the San Siro after Inter landed Martin Montoya from Barcelona earlier in the summer.
Now, Tutto Mercato Web carry a report suggesting that Inter have entered discussions with Tottenham and West Ham over possible transfers to send D'Ambrosio to England.
Tottenham aren't in desperate need of another full back having signed Kieran Trippier from Burnley earlier this summer, but concerns over Kyle Walker's fitness could force Pochettino into the market for another solution - especially if DeAndre Yedlin is loaned out.
However, West Ham released Guy Demel earlier this summer, and whilst Carl Jenkinson has returned on loan, another right back to challenge the Arsenal man could be a smart move.
Having already shopped in Italy this summer for defender Angelo Ogbonna and midfielder Pedro Obiang, West Ham could yet add another Serie A player this summer, with D'Ambrosio capable of providing competition for both Jenkinson and Aaron Cresswell in both full back positions - making a move to Upton Park more likely than White Hart Lane.