The Spain international is unsettled at the Catalan club, who have reportedly received formal enquiries from the Red Devils.
Louis van Gaal could be edging closer to his next summer signing, at least according to Spanish sports newspaper Marca, who claim that Manchester United and Barcelona are 'now negotiating' a deal for Pedro Rodriguez.
These reports come from the Madrid based outlet, despite comments from Barcelona president Josep Maria Bartomeu, following his arrival in the USA ahead of Saturday's International Champions Cup encounter between the two sides, that his club aren't planning any sales unless players submit requests to leave.
Bartomeu stressed: "We've made it clear. The team is complete, it was proposed to have the squad we have so far and we don't predict any departures. We need Pedro and this year we could win six trophies. Luis Enrique wants Pedro. We all want him here with us."
However, Bartomeu also accepted: "If anyone goes it's because the player asks to." Which now reportedly appears to be the case with Pedro, who is apparently keen to depart the Camp Nou, in his search for a more important role with another team.
There is plenty of evidence the writing is on the wall for the 27-year-old having made his decision already, indicate Marca. Not only because he wants to guarantee his place in the Spain squad for EURO 2016, which will require plenty of regular first-team action this coming season, but also based on comments from his Barcelona team-mates over recent days.
They quote Sergio Busquets as acknowledging: "I'd like Pedro to stay and to be with us for many years, but I understand he has doubts. What he wants is to play, but there's a lot of competition. We're in a team where the best players are and it's very difficult. Hopefully he stays, although it's his decision."
Likewise, Luis Suarez also feels that for Pedro: "It will be a personal decision and one he'll really need to meditate on, but I don't want him to leave." In comments noted by AS earlier this week.
As things currently stand, despite the speculation in the Spanish media, a Manchester United move for Pedro isn't perhaps as clear cut as the reports suggest.
On the one hand, Barcelona could relent to the wishes of the player and accept a €30 million Old Trafford offer. However, on the other hand the Catalan club may also stand firm, given manager Luis Enrique still feels Pedro is a part of his plans.
If the latter proves to be the case, then Barcelona can simply quote Manchester United his recently signed contract release clause of €150 million, swiftly killing any negotiations before they advance any further.
Certainly, there has been no shortage of speculation regarding the future of Pedro at Barcelona. Along with these reports claiming Manchester United are leading the chase for the Spain international, other Premier League clubs have been strongly linked.
As recently as the last seven days, whilst acknowledging the Red Devils pursuit of Pedro, the Daily Star also highlighted Chelsea, Liverpool and Arsenal, as all monitoring the situation of the player, believing they too could present bids.