Are the Tottenham Hotspur trio going to be the north London side's most important players next season?
Alderweireld's arrival at White Hart Lane could be just the medicine Vertonghen needs in the capital after a campaign that was very poor by his usual standards. The Belgian wasn't helped by a distinct lack of support from his defensive team-mates last season.
And that's where his fellow countryman and former partner at Ajax comes in. Tottenham's biggest problem last season was a very leaky back four indeed and the Alderweireld signing could see a shift in momentum in that area.
That could make the 26-year-old, along with Vertonghen, two of the most important players in Mauricio Pochettino's squad next term. They will have the hopes of the club's defensive record on their shoulders.
And another man of undoubted importance to Spurs is Harry Kane. Tottenham's summer so far suggests they will be adding minimal reinforcements up front, if any, and that they will be brought in to support the 21-year-old.
Kane, then, will be under pressure to deliver a similar standard of goalscoring to last season. That ranks him up there with Vertonghen and Alderweireld in terms of importance, as the likes of Christian Eriksen and Pochettino's midfielders can only do so much without their main man firing up front.