The 25-year-old midfielder is set to miss nearly two months with a knee problem he collected in training.
Leeds United boss Uwe Rosler has been discussing the news of Luke Murphy's knee injury in training last week on the club's website, with the midfielder now set to miss the rest of pre-season and more than likely at least some of the opening matches of the Championship.
Rosler revealed that the player was set to be out for anywhere between four and seven weeks, having already undergone a minor operation on the problem, which could see the former Crewe man out until September in a worst case scenario.
"It’s very unfortunate for Luke, I was looking forward to seeing him in action," Rosler told the Leeds site. "I rate him very highly from my time in League One when he was playing for Crewe.
"He had a strong end of the season last year and came back to training motivated.
"Everything went his way and went well until he twisted his knee with nobody around him. It’s a very unfortunate situation.
"He needed a minor operation to clear one or two things up and we expect him back within four to seven weeks."
Murphy had problems with his achilles last season that saw him also sit out a large part of the midseason, but the 25-year-old has generally been regularly involved since arriving from Gresty Road in 2013.
His 72 appearances and 6 goals indicated that Murphy would have almost certainly been a player in Rosler's forethoughts when it came to selecting his midfield, whether that would be in central or right midfield.
The German may now be tempted to continue his recruitment by considering a possible midfield option to come in either on loan or permanently, with a good start essential to the Whites having a realistic chance of making the playoffs.