The World Cup and two-time European Championship winner may well be making the switch to Old Trafford.
La Liga expert Graham Hunter, who works for Sky, said that contract discussions with Ramos had not gone well between the player and Real, despite there being two years remaining on his deal, and United have tested Real's resolve with a £28.6 bid - only to find the World Cup winner eager to make the switch to Old Trafford.
"Ramos has told Madrid directly that he is absolutely and completely committed to leaving the club this summer," Hunter told Sky Sports. "That he specifically wants them to begin negotiations with Manchester United and that he doesn't want them to negotiate with anybody except Manchester United.
"Ramos is a bold and brave footballer and that is echoed in his character. He believes the bid matches his current value.
"He looks at the project to rebuild Manchester United, to make it great again, and he wants to be part of it."
Ramos has made 445 appearances for Real since signing from Sevilla in 2005, while also winning an astonishing 128 caps for Spain, and last year turned out for Los Blancos 42 times, scoring 7 goals.
Could Ramos be a high class solution to a long-standing problem at United?
The Red Devils have long been linked with making a significant central defensive addition, with several players being rumoured to be the one that comes in and adds genuine, proven quality to the middle of the back four.
But few would have entertained that Sergio Ramos would be a realistic solution to a problem that has dogged United since Nemanja Vidic and Rio Ferdinand's form started to waver a little.
Hunter's words may only be comments from a journalist, rather than any kind of confirmation from the player or either club, but he is a high profile La Liga consultant for the UK, and at the very least it certainly throws an intriguing blanket over what is already a summer of highbrow transfer stories, with Real themselves said to be actively attempting to recruit United keeper David De Gea, according to the Mail.
If 29-year-old Ramos, arguably Real's highest profile defender, pushes for a move the other way, it may well indicate that Madrid aren't the only club that can throw their financial and historical weight around Europe.
United and Real fans may well be eagerly awaiting each day with more news from either camp, regarding what would surely be one of the transfers of the summer.