The Belgian is only on loan at the club from Atletico Madrid.
Southampton take on Aston Villa today in their final home game of what has been a surprisingly successful season.
The Saints lost many of their star players and their manager last summer to the likes of Manchester United, Liverpool, Arsenal and Tottenham Hotspur.
But new boss Ronald Koeman made some shrewd acquisitions, one of which was Toby Alderweireld.
The former Ajax defender had struggled to be a first-team regular at Atletico Madrid last season, so Southampton managed to bring him in on a season-long loan deal in the summer.
He has gone on to become a vital member of the first-team and one of the best performers at the back in the Premier League this season.
Today could indeed be his final home game for The Saints. So this morning he was on the Tweet sending out this message to his followers before going head-to-head with international team-mate for Belgium Christian Benteke at St Marys.
It is understood that Alderweireld wants a Southampton stay but at the moment it looks as though Atleti want him back. Tottenham were also linked with his signature last week by the Mirror, along with Chelsea and Manchester City.