The Bhoys inched closer to their fourth successive Scottish Premiership title triumph when they got the better of Dundee 5-0 at home.
Griffiths opened the scoring for Celtic at Celtic Park on the half-hour mark with a header, and Scott Brown doubled the advantage seven minutes later.
Kris Common made it 3-0 to Ronny Deila’s side from the penalty spot in the 71st minute, and James Forrest added a fourth with a low drive.
Celtic saved the best for the last, as Nir Bitton wrapped up a comprehensive 5-0 victory with a superb long-range effort in the 88th minute.
Griffiths was overjoyed with the win and posted the following message on Twitter after full time.
Great performance, 5 goals, clean sheet. Can't really ask for more. Another headed goal too...getting good at them. Have a good weekend— leigh griffiths (@Leighgriff09) May 1, 2015
Celtic are now 11 points clear of second-placed Aberdeen at the top of the Premiership table.
If Aberdeen fail to pick up all three points against Dundee United at Tannadice Park today, then the Hoops will win the league title.