The LA Galaxy forward is hoping to be in the All-Star line-up for July's encounter with his old club.
After touring North America last preseason, Tottenham are set to return to the States this summer as the opponents for the 2015 MLS All-Star Game, which will take place at Dick’s Sporting Goods Park – home of the Colorado Rapids.
Keane himself made 228 appearances across two spells for Spurs, scoring 112 goals before leaving in August 2011 for LA, where he has since helped the reigning MLS Cup championships win three titles in four seasons.
The Irishman recorded 19 goals and 14 assists in 29 regular-season games last term to claim the league’s MVP award and has also been named to the All-Star roster over the past two campaigns.
He was unable to feature in 2014’s 2-1 win over Bayern Munich, however, due to the Galaxy’s schedule, but is determined not to miss the match this time around if selected.
"To play against your former team and some former team-mates is certainly exciting," he said. "I know the whole MLS league is excited to have Tottenham come over and play against us.
"It is certainly a club that I am remembered for most really and I've certainly got great memories at Tottenham.
"You can now see how the league has grown, certainly with the players coming over here like Kaka and Stevie Gerrard,” he added.
"The league will only continue to grow and I believe in the next five, six years it could be a massive, massive league."
Keane might not be the only ex-Spurs player on the All-Star roster come July either, with Seattle Sounders forward Clint Dempsey a good bet to make the team too, fitness providing.
In addition, the match could also see Dempsey face off against his former Seattle teammate DeAndre Yedlin, who completed his pre-arranged move to Tottenham this winter after making the All-Star team in his first two professional seasons.