Sunderland were beaten 4-1 by Palace and their collapse visibly frustrated Cattermole, who seemed to lose his discipline.
The combative midfielder picked up a booking for a foul and his lack of restraint after this yellow caused Advocaat to withdraw him from the action before he was given his marching orders.
“I took him off in case something happened because he was really frustrated,” he said.
The comments are worrying because this is an area that Cattermole has worked hard on improving over the last few seasons.
The 27-year-old has always played on the edge and his aggression is what has made him such a successful player, but he has shown more signs of caution recently.
In Cattermole's 227-game Premier League career he has picked up 76 yellows and seven reds, and Advocaat's comments would suggest that he still hasn't entirely learned to curb his temper.
It could be a worry with the pressure mounting on Sunderland's season and the hope will be that Cattermole does not have to be taken off again, as he is one of their most integral players when fully focused.