Pundit Mark Lawrenson has predicted in his column for the BBC that Manchester United and Manchester City will draw later today.
United are in fine form having won each of their last five games, including the 3-1 win over Aston Villa at Old Trafford last weekend.
With Wayne Rooney playing up front again, Marouane Fellaini emerging in midfield as well as having Ander Herrera and Juan Mata firing on all cylinders, Louis van Gaal finally seems to have found the right balance in his team - and recent results have been superb, especially the 2-1 win against Liverpool at Anfield last month.
Conversely, City are going through a real rocky patch, and with three defeats in their last five games, their title bid has fallen apart.
Manager Manuel Pellegrini is under huge pressure after Monday's 3-1 defeat to Crystal Palace, and fans are hoping that the Chilean can turn things around against their bitter rivals United.
That will be a tough task considering the respective form of the two sides, but Lawrenson wrote for the BBC that he expects a tight game - and ultimately a 1-1 draw at Old Trafford.
"Manchester United are on a very good run and their fans are suddenly all shouting about how they are going to finish above Manchester City," said Lawrenson. "On current form, it looks like they might be right because United have been playing very well in recent weeks. City, clearly, have not."
"But this is a huge game for them and I think we will see City's big players like Yaya Toure rise to the occasion. They have done that enough times at Old Trafford in the recent past - City have won on their last three visits. I am expecting a closer encounter this time and I think it is going to end in a draw after an open game," he added.
Pellegrini should be able to call upon the likes of Toure, David Silva and Sergio Aguero, but all three will need to be on top form if City are to beat United at Old Trafford yet again.