Manchester United are enjoying a rare period of ascendancy over their cross-city rivals in recent times, so how have they fared in the last five derbies?
Sunday's Manchester match-up sees Louis van Gaal's men in third spot, a point above City in the last Champions League place. Both clubs look comfortable in the coveted top four bracket, but City will be anxious to address a rare slip in their dominance of the last few years and record a fourth straight win at Old Trafford.
In the build-up to Sunday's game we look back at the last five Old Trafford meetings, all of which have proved pivotal in the title race.
20th September 2009 Manchester United 4 Manchester City 3
Best remembered as the 'Michael Owen' game, it was undoubtedly the former England man's defining moment as a Manchester United player. In a dramatic game that never let-up Alex Ferguson's men took the lead three times, but City hit back each time, and Craig Bellamy's 90th minute equaliser appeared to have saved the day for City again. But Owen popped up deep into stoppage time with a typical drilled finish that sent Old Trafford wild.
12th February 2011 Manchester United 2 Manchester City 1
With both sides challenging at the top of the table again, it was a crucial meeting at Old Trafford. Nani gave Manchester United a first half lead and David Silva equalised for City when he deflected an Edin Dzeko shot fortuitously. But on 78 minutes Wayne Rooney settled the contest when he scored one of the best goals this famous fixture has ever seen. Rooney saw a Nani cross dipping behind him and turned acrobatically to whip an overhead kick past a stunned Joe Hart for a sensational winner.
23rd October 2011 Manchester United 1 Manchester City 6
Probably the most notorious result ever in this fixture, but it was a tight contest up until Johnny Evans' 47th-minute sending off for the home side. Mario Balotelli had given City a 1-0 half-time lead but after the sending off, goals from Balotelli again and Sergio Aguero stretched City's lead as they homed in on their first Premier League title. When Darren Fletcher pulled a goal back in the 81st-minute the score looked respectable, but City piled on the agony with three goals in stoppage time to record a famous and highly significant victory.
8th April 2013 Manchester United 1 Manchester City 2
Manchester United were back in the driving seat and heading towards a straightforward Premier League crown when the two sides met at Old Trafford for the first time since that 6-1 victory the previous season. However, it was City who enjoyed a rare success amid a disappointing title defence. All the action was in the second half, as James Milner gave City the lead only for a Vincent Kompany own goal to bring the scores level eight minutes later. But it was Argentine striker Sergio Aguero who settled the game with a brilliant solo run and shot in the 78th minute.
25th March 2014 Manchester United 0 Manchester City 3
The home side were not involved in one of the most open title races in years, and when City visited in this late season clash they were chasing both Liverpool and Chelsea above them. An early Edin Dzeko strike set them off on a routine victory over David Moyes' struggling side, and second half goals from Dzeko again and Yaya Toure settled the contest. City went on to claim their second Premier League crown and Manchester United were left to lick their wounds after being systematically brushed aside.