The Wanderers will host the West Yorkshire out at Molineux in the Championship.
Wolves are having a great season and are in contention of a top-six finish, but Leeds are expected to pose a strong challenge.
Although the Whites lost 3-0 to Blackburn Rovers at Elland Road, they have a team who can pick up all three points at Molineux.
Jackett seems to be fully aware of that and has urged his players to get the Wolves fans behind them right from the start.
“For us now our responsibility is to really try to get a big and passionate crowd behind us,” the 53-year-old told The Birmingham Mail.
“Only our performance level, our quality, hunger and desire will do that, but that’s our responsibility. It has to be our focus because if we can get the crowd going it will drive us on.”
Wolves are currently eighth in the Championship table with 68 points from 40 matches, level on points with sixth-placed Derby County and behind only on goal difference.
Meanwhile, Leeds find themselves 14th in the league standings at the moment with 52 points from 40 matches.