The Italian defender is set to join the Nerazzurri for a fee believed to be in the €3 million region.
The attack-minded full-back has been an impressive feature of the St James’ Park side for a number of seasons, but it now appears that he will leave Tyneside permanently.
Santon’s agent Renzo Contratto has admitted that the deal to take the left-back to the Stadio Giuseppe Meazza permanently has been agreed.
“Let's say that Inter's purchase is now official,” he told La Gazzetta dello Sport.
“It was an ideal return to Milan and we are satisfied. It's a shame that it does not correspond to the team's results.
“He played 100 games in the Premier League, the top championship in the world, so it's normal that he developed. And he can develop even further.”
Newcastle’s willingness to part company with one of their best players will surely be a concern for the Geordie faithful, with Santon one of the best attacking full-backs in the Premier League when on form.
The report also instigates that a fee in the €3 million is enough to take Santon back to his homeland. Neither club has yet confirmed the deal.
The 24-year-old left the Milan-based outfit to join Newcastle in the summer of 2011 and became a mainstay at the Tyneside club over a number of seasons.
However, the draw of home and reduced playing time at St James' Park motivated a return to the Nerazzurri, where he has started five Serie A games since a January loan move.