Tottenham's captain couldn't hide his disappointment after the Old Trafford defeat.
Lloris didn't actually have much to do in the game, with United's three goals coming from their three on-target efforts, but having to pick the ball out of the back of the net three times in the opening half isn't something the France international has been subjected to too often his season.
The former Lyon man is used to being able to make a difference in his side's ability to stop opponents from scoring, but all three United goals left little chance for the 28-year-old to keep his team in the game.
After the match, Tottenham's visibly disappointed skipper told Viasat that the result could help the players improve, as long as they discussed it honestly with each other.
"There are still 9 games to go," Lloris said. "There a lot of things to learn and we need to talk all together to carry on and try to get as much points as possible until the end of the season. We need to carry on.
"It's not about fatigue, it's about character, about [being] men. This is why as I said we need to learn about this game, to tell the truth and find the winning way next game at home."
Spurs may have always looked at the match against United as their toughest remaining fixture, so if anything, the manner of the defeat will hurt more than the fact they didn't manage to take any points away from the match.
As Lloris said, their next game will be hosting Leicester City at White Hart Lane, where the Foxes knocked Spurs out of the FA Cup, and that will be the time when supporters will be hoping to see a reaction.