The young striker came off 40 minutes into the fixture with Everton's under-21s in Southport.
Toward the end of last season James Wilson made his impact at Manchester United. He scored two goals on his debut against Hull City in May last year, truly a shining breakthrough.
This season has seen him push on again. Radamel Falcao's arrival has not massively disrupted his development, playing 16 times this season scoring twice - against QPR and Cambridge United.
His performances have impressed again and today he was in good form for the under-21 side.
Wilson was in the team that faced Everton this evening, and he did what he did best. He scored in the game, netting a rebound after Russell Griffiths had parried a strike from Andreas Pereira.
However, the performance came at a cost.
Wilson limped out of the game in the 40th minute. The Manchester Evening News is reporting that he suffered a hamstring injury in the game and looks a concern for the game with Liverpool this weekend, as reported by Manchester Evening News.
With Robin van Persie also out of action for the rest of the month United could find themselves with just two fully-fit strikers for the next couple of weeks.
The good news, there will surely be no way Manchester United employ Wayne Rooney in a midfield position at this rate, leaving him free to score goals for fun at Old Trafford.