Barcelona will be missing three starters when they travel to the Basque Country to face Eibar for a first meeting in the club's history, with Sergio Busquets, Dani Alves and Jordi Alba all unavailable.
Busquets continues to struggle with an ankle injury suffered in Barcelona's Copa del Rey win over Villarreal two weeks ago and is a serious doubt to figure in the second leg of next week's decisive Champions League last-16 tie with Manchester City at the Camp Nou.
Barcelona manager Luis Enrique will also be without two of his most utilised and consistent defenders, as both left-back Alba and right-back Alves are serving one match bans, leaving them free to face Real Madrid in next weekend's El Clasico.
However, despite the loss of several key players, Enrique has chosen not to call up any Barcelona B players, with Munir, Sandro Ramirez and Diagne having spent time in first team training throughout the week.
Alves is likely to be replaced by Martin Montoya, while Alba will be replaced by either Adriano or Jeremy Mathieu, who has played as both centre-back and left-back this season.
Barcelona's 18-man squad for their match against Eibar is as follows:
Goalkeepers:Marc Andre Ter Stegen and Claudio Bravo
Defenders:Martin Montoya, Douglas, Adriano, Marc Bartra, Gerard Piqué, Javier Mascherano and Jeremy Mathieu.
Midfielders:Ivan Rakitic, Xavi, Sergi Roberto, Andres Iniesta and Rafinha.
Forwards:Pedro, Leo Messi, Neymar and Luis Suárez.