The former Manchester United star wants to get one over old pal Rio Ferdinand.
QPR, on the other hand, are in a relegation battle and will be hoping to get one over on the top-four chasing Gunners at their home ground.
For one Arsenal player it is a chance to go head-to-head with a former Manchester United team-mate. Danny Welbeck left United for Arsenal in the summer, while Rio Ferdinand left for QPR.
Today they could face off and Welbeck has been discussing his close personal relationship with Rio on the official Arsenal site today, stating:
“Me and Rio are pretty close. I still speak to him today. Coming through United as a young kid, Rio was there for me a lot giving advice, as were all the other older players. It will be good to play against him in a competitive game.
“You don’t really need any extra motivation - you always want to go out and get that win, beat your man, and you always want to get the better of whoever you’re playing against.
“However, having that relationship on the pitch with somebody you know quite well means you want to beat them even more and sometimes there’s a bit of banter on the pitch as well."
Of course the two clashing will rely heavily on team selection. Ferdinand struggled initially after his move to QPR and before he resigned, Harry Redknapp had taken him out of the first-team.
However, new boss Chris Ramsey has used him recently and the veteran's experience of facing top class attacking talent may see him brought into the fold once again.
Welbeck, on the other hand, returned from injury earlier in the month and has featured in every game since, including a late substitute appearance against Everton on Sunday.
He will be hoping that he and Rio both start this evening, so he can try and get one over on his old mate.