Most other years, the Blues would be heavy favourites, but this season Tottenham are the ones that most recently shone in a fixture between the two sides.
For the first time in years, Spurs players will know they can beat Chelsea
There are few teams in the Premier League era that have dominated Tottenham as much as Chelsea. Wins are few and far between for the North London side, especially away from White Hart Lane.
That all changed this season, not just with the massive win in January but also a decent performance at Stamford Bridge last year, even if it did end up with a comfortable win for Chelsea.
Of course one famous win that Spurs have managed outside of the Premier League is the League Cup final triumph in 2008, but since then Chelsea have had their revenge in the latter stages of the FA Cup.
But it is the astonishing five goals scored during their victory over Mourinho's men on New Year's Day that will really help the men in white believe. The Spurs attackers will start the game knowing that they can damage the Blues, and may even have personal tricks they employed to great effect that they can try once more. If they can replicate their form from the 5-3 win in any way, Terry and co are likely to struggle.
The absence of Nemanja Matic
Much discussed in the lead up to the final, the sending off of the Serbian anchorman against Burnley last weekend provoked an extraordinary reaction by Jose Mourinho, with the Chelsea boss ramping up his campaign promoting the notion that his side are harshly affected by poor refereeing decisions. Whether Matic should be suspended or not, Chelsea will be missing a player who has arguably been one of the best defensive midfielders in Europe this season, and with Mourinho admitting that John Obi Mikel is also set to miss the final through injury, it strips the Blues of their two most natural holding players in the middle of the park - something the likes of Christian Eriksen will be hoping to exploit.
The central defence could, and should, be fearful of Harry Kane
Normally such a bastion of strength for the Blues, and any Jose Mourinho side, it has been a long time since a team took apart John Terry and Gary Cahill in the manner Spurs did on New Year's Day. Nacer Chadli and Harry Kane in particular gave both players a game they won't forget in a hurry. Such was the extent of Kane's destruction of Cahill, young defender Kurt Zouma has been given a much more pronounced role in the Chelsea side in the fixtures since. Kane has continued his impressive form since that brace, with another double against Arsenal a particular highlight, and his late, late equaliser against West Ham last week. Much of Tottenham's hopes will be resting on his young, but broad Lilywhite shoulders.