The Gunners have failed to progress to the Champions League quarter-finals in four years but have been handed a great opportunity this season after being paired against French side Monaco.
Arsene Wenger’s men initially finished second in their group behind winners Borussia Dortmund, thus big names such as Real Madrid, Barcelona and Bayern Munich were all possible last 16 opponents.
However, the North Londoners were handed a favourable tie and Welbeck has urged his teammates to play to their strengths on the day and let the result take care of itself.
"We're all looking forward to playing against Monaco. Any team you get in the Champions League will be a difficult opponent and it will be no different with Monaco,” Welbeck explained.
"They have strong players and it's going to be a big challenge for us. At this level, every match you play is going to be a challenge but all the players enjoy it.
"We just need to be strong on the day and play to our strengths. We have great players here and a great spirit in the squad, so we are looking forward to the challenge."
Favourites to reach the quarter-finals?
On current form, Arsenal arguably rank as big favourites to reach the last eight and failing to do so would prove a huge disappointment both for the players and supporters.
Unlike the French side, the Gunners have plenty of big-game experience and the challenges of the Premier League can only help their task unlike a rather weak French top flight.
Arsene Wenger’s side’s recent victory over Manchester City has raised the expectation levels at the Emirates and big questions will be asked if Monaco are to get the best of them in the coming weeks.