The Barcelona pair have been in blistering goalscoring form this term and could well hit a joint landmark figure.
Barcelona have won 11 consecutive games in all competitions this year and are arguably the form team in Europe at the moment.
The Argentina international has netted 37 goals in all competitions this season, while the Brazilian has struck 24 times.
With Neymar just needing six more goals to ensure both end the season with at least 30 goals apiece, the duo could set a personal record that has only been matched once before.
Only once "2" Barcelona players managed to score 30+ goals in the same season 2008/09: Messi (38) & Eto'o (36) 2014/15: Messi 37, Ney 24 =)— Barça (@BarcaStat) February 21, 2015
As can be seen above, Messi and Samuel Eto’o both struck more than 30 goals each in the 2008-09 season but this feat has not been achieved by another Blaugrana pair.
With Barcelona hosting Malaga today, the pair will get a chance to increase their collective goal tally and temporarily go top of the league ahead of Real Madrid’s fixture against Elche on Sunday.
Barcelona travel to England next week to take on Manchester City in the Champions League on Tuesday night, with Messi and Neymar key in the side’s chances of overcoming Manuel Pellegrini’s side.