The Hammers are coming off last weekend's embarrassing 4-0 defeat to West Brom in the FA Cup, whilst results haven't been much better in the league of late either, with just one win in the last eight games.
Manager Sam Allardyce is now under pressure again, but will be hoping to claim back some pride with a win over Tottenham this season.
The sides met on the opening day of the season, and that finished 1-0 to Spurs thanks to a last gasp Eric Dier goal after Mark Noble had missed a penalty for West Ham.
Noble should be in the Hammers side when the teams meet on Sunday, and he spoke to the West Ham official website ahead of the encounter - singling out Spurs duo Christian Eriksen and Harry Kane for praise.
"We won there twice last season and we'd love to make it three in a row, but it will not be easy by any stretch," said Noble. "I think they are a different team now. Mauricio Pochettino has got them playing very well and obviously they've got the likes of Christian Eriksen and Harry Kane is flying now."
"They've got a good team and a good squad and it's going to be tough, so we need to go there and play our best game, or else we'll get turned over," he added.
Danish international playmaker Eriksen has hit nine goals in 25 Premier League games this season, establishing himself as the heartbeat of Pochettino's midfield this season, whether it's in a No. 10 role or out on the left hand side.
Meanwhile, striker Kane has arguably been the star of the season, emerging as one of the most promising young English strikers around.
23 goals in all competitions means that the 21-year-old is the name on everybody's lips right now, so West Ham will have to try and keep him quiet if they have any hope of winning this game and turning around a disappointing run of form.