The Sky Sports pundit does not have high hopes for the rest of Queens Park Rangers' campaign.
But, while Merson is backing Southampton to beat QPR at Loftus Road, he also feels the west London side will continue their losing streak away from home - and that it will last the whole campaign.
"The QPR situation is rocky. They're second-bottom, brought nobody in and got rid of Jordon Mutch. I just don't really get that. It's probably why Harry Redknapp left," the former Premier League midfielder said.
"I don't think QPR have a chance of staying up, especially with the managerial situation. I also don't see them winning an away game between now and the end of the season, 11 on the trot is an unbelievable record. Their next lot of home games are against the top teams so I think they'll find it a trouble."
Merson's comments, of course, may be a little biased towards Redknapp - many feel the former QPR boss is to blame for the side's current malaise rather than a victim of it.
But the ex-midfielder is well within his rights to criticise QPR's away record. Southampton, meanwhile, will feel confident of their chances at Loftus Road.
That said, Ronald Koeman's high-flying Saints did lose at home to Swansea City last weekend and could slip out of the top four should their trip to the capital go against them.
In terms of their record on the road, however, Southampton are on fire, having picked up several away wins in recent weeks.