This time, Louis van Gaal's side swept Leicester aside, hammering Nigel Pearson's men 3-1 in a convincing victory at Old Trafford.
Robin van Persie got the ball rolling for the Red Devils on 27 minutes, turning the ball into the net from a superb lofted pass by midfielder Daley Blind.
Strike partner Radamel Falcao then made it two just five minutes later, bundling the ball home from close range after Angel Di Maria's shot had been saved.
And before half time, it became 3-0, with Leicester defender Wes Morgan heading into his own net from a United corner - leaving the Foxes down and out at the break.
They did salvage some respect with Marcin Wasilewski pulling a goal back late on, but United claimed the three points, moving them just four points behind rivals Manchester City in the Premier League table, whilst Leicester remain rooted to the bottom of the league.